Gene expression profile and cytotoxicity of human bronchial epithelial cells exposed to crotonaldehyde.

@article{Liu2010GeneEP,
  title={Gene expression profile and cytotoxicity of human bronchial epithelial cells exposed to crotonaldehyde.},
  author={Xing-yu Liu and Zhihua Yang and Xiu-jie Pan and Mao-xiang Zhu and Jian-ping Xie},
  journal={Toxicology letters},
  year={2010},
  volume={197 2},
  pages={113-22}
}
Crotonaldehyde is an environment pollutant and lipid peroxidation product. Crotonaldehyde produces adverse effects to humans and serves as a risk factor for human pulmonary diseases. Like acrolein and 4-hydroxynonenal, crotonaldehyde seems likely to alter many cell signaling cascades, including inflammatory responses. The purpose of this study was to investigate the genome-wide transcriptional responses of normal human bronchial epithelial cells exposed to crotonaldehyde. Using microarrays… CONTINUE READING
5 Citations
56 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 56 references

Xenobiotic oxidationcatalyzedbyaldehydedehydrogenases

  • D. tagos, Y. Chen, M. Cantore, J. V. Jester, V. Vasiliou
  • DrugMetab . Rev .
  • 2010

Cigarette smokeinducedneurogenic inflammation is mediated by alpha , betaunsaturated aldehydes and the TRPA 1 receptor in rodents

  • E. eferences ndre, B. Campi, +11 authors R. Patacchini
  • J . Clin . Invest .
  • 2008

Detoxification of promutagenic aldehydes derived from methylpyrenes by human aldehyde dehydrogenases ALDH 2 and ALDH 3 A 1

  • A. L. Goldberg
  • Arch . Biochem . Biophys .
  • 2008

Similar Papers

Loading similar papers…