Gene expression profile and aortic vessel distensibility in voluntarily exercised spontaneously hypertensive rats: potential role of heat shock proteins.

@article{Hgg2005GeneEP,
  title={Gene expression profile and aortic vessel distensibility in voluntarily exercised spontaneously hypertensive rats: potential role of heat shock proteins.},
  author={Ulrika H{\"a}gg and Maria E Johansson and Julia Gr{\"o}nros and Andrew S. Naylor and Ingibj{\"o}rg H Jonsdottir and G{\"o}ran Bergstr{\"o}m and Per-Arne Svensson and Li-ming Gan},
  journal={Physiological genomics},
  year={2005},
  volume={22 3},
  pages={319-26}
}
Physical exercise is considered to be beneficial for cardiovascular health. Nevertheless, the underlying specific molecular mechanisms still remain unexplored. In this study, we aimed to investigate the effects of voluntary exercise on vascular mechanical properties and gene regulation patterns in spontaneously hypertensive rats. By using ultrasound biomicroscopy in an ex vivo perfusion chamber, we studied the distensibility of the thoracic aorta. Furthermore, exercise-induced gene regulation… CONTINUE READING
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