Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells

@inproceedings{OliveiraCosta2015GeneEP,
  title={Gene expression patterns through oral squamous cell carcinoma development: PD-L1 expression in primary tumor and circulating tumor cells},
  author={Jo{\~a}o Paulo Oliveira-Costa and Alex Fiorini de Carvalho and Gi{\'o}rgia Gobbi da Silveira and Peter Amaya and Yongqi Wu and K Park and Mabel Pinilla Gigliola and Maryam Lustberg and Marcilei Eliza Cavicchioli Buim and Elisa Napolitano e Ferreira and Luiz Paulo Kowalski and Jeffrey J Chalmers and Fernando Augusto Soares and Dirce Maria Carraro and Alfredo Ribeiro-Silva},
  booktitle={Oncotarget},
  year={2015}
}
Oral squamous cell carcinoma (OSCC) is the most common tumor of the oral cavity and has been associated with poor prognosis. Scarce prognostic markers are available for guiding treatment and/or sub-classifying patients. This study aims to identify biomarkers by searching for genes whose expression is increased or decreased during tumor progression (through T1 to T4 stages). Thirty-six samples from all tumor size stages (from T1 to T4) were analyzed using cDNA microarrays. Selected targets were… CONTINUE READING
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