Gene expression patterns of murine dentin matrix protein 1 (Dmp1) and dentin sialophosphoprotein (DSPP) suggest distinct developmental functions in vivo.

@article{DSouza1997GeneEP,
  title={Gene expression patterns of murine dentin matrix protein 1 (Dmp1) and dentin sialophosphoprotein (DSPP) suggest distinct developmental functions in vivo.},
  author={Rena N D'Souza and Adriana C. Cavender and Gulshan Sunavala and Jes{\'u}s Rom{\'a}n Mart{\'i}nez {\'A}lvarez and Takayuki Ohshima and Ashok Kulkarni and Mary Macdougall},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={1997},
  volume={12 12},
  pages={2040-9}
}
Although the precise mechanisms of the conversion of predentin to dentin are not well understood, several lines of evidence implicate the noncollagenous proteins (NCPs) as important regulators of dentin biomineralization. Here we compared the in vivo temporospatial expression patterns of two dentin NCP genes, dentin matrix protein 1 (Dmp1), and dentin sialophosphoprotein (DSPP) in developing molars. Reverse transcription-polymerase chain reaction was performed on embryonic day 13 to 1-day-old… CONTINUE READING

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