Gene expression patterns in the hypoxic murine placenta: a role in epigenesis?

@article{Gheorghe2007GeneEP,
  title={Gene expression patterns in the hypoxic murine placenta: a role in epigenesis?},
  author={Ciprian P Gheorghe and Subburaman Mohan and Kerby C Oberg and Lawrence D. Longo},
  journal={Reproductive sciences},
  year={2007},
  volume={14 3},
  pages={223-33}
}
Hypoxia has been identified as a major stress or in placental and fetal development. To test the hypothesis that hypoxic stress responses are associated with gene expression changes, the authors measured gene expression in the mouse placenta in response to 48 hours of hypoxia. Embryonic day 15.5 pregnant mice were exposed to 48 hours of hypoxia (10.5% O(2)), after which the Affymetrix Mouse 430A_2.0 array was used to measure gene expression changes in the placenta. The authors observed 171… CONTINUE READING

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