Gene expression patterns in the bone tissue of women with fibrous dysplasia.

@article{Kiss2010GeneEP,
  title={Gene expression patterns in the bone tissue of women with fibrous dysplasia.},
  author={J{\'a}nos Kiss and Bernadett Balla and J{\'a}nos P{\'a}l K{\'o}sa and Adrienn {\'E} Borsy and J{\'a}nos Podani and Istv{\'a}n Tak{\'a}cs and {\'A}ron Lazary and Zsolt R. Nagy and Kriszti{\'a}n B{\'a}csi and Adri{\'a}n Kis and Eszter Szl{\'a}vy and Mikl{\'o}s A. Szendrői and G{\'a}bor Speer and L{\'a}szl{\'o} Orosz and Peter Lakatos},
  journal={American journal of medical genetics. Part A},
  year={2010},
  volume={152A 9},
  pages={
          2211-20
        }
}
Fibrous dysplasia is an isolated skeletal disorder caused by a somatic activating mutation of GNAS gene with abnormal unmineralized matrix overproduction and extensive undifferentiated bone cell accumulation in the fibro-osseous lesions. The aim of our investigation was to identify genes that are differently expressed in fibrous versus non-fibrous human bone and to describe the relationships between these genes using multivariate data analysis. Six bone tissue samples from female patients with… CONTINUE READING