Gene expression patterns in isolated keloid fibroblasts.

@article{Satish2006GeneEP,
  title={Gene expression patterns in isolated keloid fibroblasts.},
  author={L Deshmane Satish and James Lyons-Weiler and Patricia A. Hebda and Alan Wells},
  journal={Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society},
  year={2006},
  volume={14 4},
  pages={
          463-70
        }
}
Keloid scars after skin trauma are a significant clinical problem, especially in black populations, in which the incidence of keloids has been estimated at 4-16%. Keloids are abnormal dermal proliferative scars secondary to dysregulated wound healing. Despite several biochemical studies on the role of extracellular matrix proteins and growth factors during keloid formation, we still do not know what molecules and signals induce this change. Fibroblasts are thought to be the major inductive cell… CONTINUE READING
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