Gene expression patterns in ependymomas correlate with tumor location, grade, and patient age.

@article{Korshunov2003GeneEP,
  title={Gene expression patterns in ependymomas correlate with tumor location, grade, and patient age.},
  author={Andrey Korshunov and Kai Neben and Gunnar Wrobel and Bj{\"o}rn Tews and Axel Benner and Meinhard Hahn and Andrey Golanov and Peter Lichter},
  journal={The American journal of pathology},
  year={2003},
  volume={163 5},
  pages={1721-7}
}
To elucidate the molecular events responsible for tumorigenesis and progression of ependymomas, we analyzed molecular alterations on the gene expression level in a series of newly diagnosed ependymal neoplasms (n = 39). To this aim, tumor RNA was hybridized to microarrays comprising 2600 different genes with relevance to mitosis, cell-cycle control, oncogenesis, or apoptosis. For CLU, IGF-2, and RAF-1, which are apparent candidate genes because they had been previously described to be involved… CONTINUE READING

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