Gene expression of the phosphodiesterases 3A and 5A in human corpus cavernosum penis.

@article{Kthe2000GeneEO,
  title={Gene expression of the phosphodiesterases 3A and 5A in human corpus cavernosum penis.},
  author={Andrea K{\"u}the and H J M{\"a}gert and Stefan Uckert and Wolf Georg Forssmann and Christian G Stief and Udo Jonas},
  journal={European urology},
  year={2000},
  volume={38 1},
  pages={108-14}
}
OBJECTIVE The following study was performed to evaluate the importance of phosphodiesterases 3A (PDE3A) and 5A (PDE5A) for the regulation of penile smooth muscle tone. Furthermore, indications of side effects of specific inhibitors in certain tissues as well as of a possible relation between the level of PDE3A and PDE5A gene expression and erectile dysfunction should have been deduced from the results obtained. METHODS Total ribonucleic acid was isolated from different human tissues… CONTINUE READING

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