Gene expression of gastric type mucin (MUC5AC) in pancreatic tumors: its relationship with the biological behavior of the tumor.

@article{Yonezawa1999GeneEO,
  title={Gene expression of gastric type mucin (MUC5AC) in pancreatic tumors: its relationship with the biological behavior of the tumor.},
  author={Suguru Yonezawa and Michiko Horinouchi and Masahiko Osako and Makoto Kubo and Sonshin Takao and Yoshiaki Arimura and Koji Nagata and Sadao Tanaka and Koro Sakoda and Takashi Aikou and Elichi Sato},
  journal={Pathology international},
  year={1999},
  volume={49 1},
  pages={45-54}
}
Previously it has been found that the MUC2 gene for intestinal type secretory mucin is highly expressed in intraductal papillary mucinous tumors (IPMT), which are characterized by non-invasive growth and a favorable outcome. In contrast, MUC2 mRNA is rarely expressed in invasive ductal carcinomas (IDC), which have poor outcomes. The gastric type secretory mucin, MUC5AC, is strongly expressed in the surface mucous cells of gastric mucosa. As both MUC2 and MUC5AC mucins share the characteristics… CONTINUE READING

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