Gene expression of estrogen receptor, progesterone receptor and microtubule-associated protein Tau in high-risk early breast cancer: a quest for molecular predictors of treatment benefit in the context of a Hellenic Cooperative Oncology Group trial

@article{Pentheroudakis2008GeneEO,
  title={Gene expression of estrogen receptor, progesterone receptor and microtubule-associated protein Tau in high-risk early breast cancer: a quest for molecular predictors of treatment benefit in the context of a Hellenic Cooperative Oncology Group trial},
  author={George Pentheroudakis and Konstantine T. Kalogeras and Ralph Markus Wirtz and Irene Grimani and George N. Zografos and Helen J. Gogas and Udo Stropp and Dimitrios Pectasides and Dimosthenis V. Skarlos and Guido Hennig and Epaminondas Samantas and Dimitrios Bafaloukos and Pavlos Papakostas and Haralambos P. Kalofonos and Nicholas Pavlidis and George Fountzilas},
  journal={Breast Cancer Research and Treatment},
  year={2008},
  volume={116},
  pages={131-143}
}
  • George Pentheroudakis, Konstantine T. Kalogeras, +13 authors George Fountzilas
  • Published in
    Breast Cancer Research and…
    2008
  • Medicine
  • Background Estrogen receptor (ER) and progesterone receptor (PgR) protein expression carry weak prognostic and moderate predictive utility for the outcome of early breast cancer patients on adjuvant chemohormonotherapy. We sought to study the predictive significance and correlations of transcriptional profiling of the ER, PgR and microtubule-associated protein Tau (MAP-Tau) genes in early breast cancer. Materials and methods Messenger RNA (mRNA) was extracted from 279 formalin-fixed paraffin… CONTINUE READING

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