Gene expression of endoplasmic reticulum resident selenoproteins correlates with apoptosis in various muscles of se-deficient chicks.

@article{Yao2013GeneEO,
  title={Gene expression of endoplasmic reticulum resident selenoproteins correlates with apoptosis in various muscles of se-deficient chicks.},
  author={Hai-dong Yao and Qiong Wu and Zi-wei Zhang and Jiu-li Zhang and Shu Li and Jia-Qiang Huang and Fazheng Ren and Shi-wen Xu and Xiaolong Wang and Xin Gen Lei},
  journal={The Journal of nutrition},
  year={2013},
  volume={143 5},
  pages={613-9}
}
Dietary selenium (Se) deficiency causes muscular dystrophy in various species, but the molecular mechanism remains unclear. Our objectives were to investigate: 1) if dietary Se deficiency induced different amounts of oxidative stress, lipid peroxidation, and cell apoptosis in 3 skeletal muscles; and 2) if the distribution and expression of 4 endoplasmic reticulum (ER) resident selenoprotein genes (Sepn1, Selk, Sels, and Selt) were related to oxidative damages in these muscles. Two groups of day… CONTINUE READING
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