Gene expression of atrial natriuretic peptide in rat papillary muscle. Rapid induction by mechanical loading.

@article{Jarygin1994GeneEO,
  title={Gene expression of atrial natriuretic peptide in rat papillary muscle. Rapid induction by mechanical loading.},
  author={C Jarygin and Joerg Haenze and Rudolf E. Lang},
  journal={FEBS letters},
  year={1994},
  volume={346 2-3},
  pages={185-8}
}
The effect of mechanical stretch on protein synthesis and the expression of the gene for atrial natriuretic peptide (ANP) was examined in electrically paced, isolated papillary muscles from rat heart. Incorporation of [3H]phenylalanine into protein increased only in stretched but not in unloaded muscles. Five hours of stretching increased ANP mRNA levels… CONTINUE READING