Corpus ID: 5888934

Gene expression in thiazide diuretic or statin users in relation to incident type 2 diabetes.

  title={Gene expression in thiazide diuretic or statin users in relation to incident type 2 diabetes.},
  author={Astrid M. Suchy-Dicey and S. Heckbert and N. Smith and B. McKnight and J. Rotter and Y. I. Chen and B. Psaty and D. Enquobahrie},
  journal={International journal of molecular epidemiology and genetics},
  volume={5 1},
Thiazide diuretics and statins are used to improve cardiovascular outcomes, but may also cause type 2 diabetes (T2DM), although mechanisms are unknown. Gene expression studies may facilitate understanding of these associations. Participants from ongoing population-based studies were sampled for these longitudinal studies of peripheral blood microarray gene expression, and followed to incident diabetes. All sampled subjects were statin or thiazide users. Those who developed diabetes during… Expand
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