Gene expression in the prefrontal cortex during adolescence: implications for the onset of schizophrenia

@article{Harris2008GeneEI,
  title={Gene expression in the prefrontal cortex during adolescence: implications for the onset of schizophrenia},
  author={Laura Wiseman Harris and Helen E. Lockstone and Philipp Khaitovich and Cynthia Shannon Weickert and Maree J. Webster and Sabine Bahn},
  journal={BMC Medical Genomics},
  year={2008},
  volume={2},
  pages={28 - 28}
}
Many critical maturational processes take place in the human brain during postnatal development. In particular, the prefrontal cortex does not reach maturation until late adolescence and this stage is associated with substantial white matter volume increases. Patients with schizophrenia and other major psychiatric disorders tend to first present with overt symptoms during late adolescence/early adulthood and it has been proposed that this developmental stage represents a "window of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 48 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 89 references

Similar Papers

Loading similar papers…