Gene expression in human neutrophils during activation and priming by bacterial lipopolysaccharide.

@article{Tsukahara2003GeneEI,
  title={Gene expression in human neutrophils during activation and priming by bacterial lipopolysaccharide.},
  author={Yasuhiro Tsukahara and Zheng Lian and Xueqing Zhang and Constance B Whitney and Yuval Kluger and David F. Pyke Amos Tuck and Shigeru Yamaga and Yasuhiro Nakayama and Sherman Morton Weissman and Peter E Newburger},
  journal={Journal of cellular biochemistry},
  year={2003},
  volume={89 4},
  pages={848-61}
}
Circulating neutrophils play a key role both in the systemic inflammatory response and in complications of bacterial infection such as septic shock and septic multiple organ dysfunction syndrome. We have analyzed gene expression patterns in human neutrophils stimulated by E. coli lipopolysaccharide (LPS), with or without prior exposure to LPS, using differential display and oligonucleotide chip techniques. We identified 307 genes that were activated or repressed after treatment with LPS at 10… CONTINUE READING

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