• DOI:10.1152/physiolgenomics.2001.6.3.169
Corpus ID: 9296949

Gene expression following acute morphine administration.

@article{Loguinov2001GeneEF,
  title={Gene expression following acute morphine administration.},
  author={Alexander V. Loguinov and Lucy M. Anderson and Gregory J. Crosby and Rustam Yu. Yukhananov},
  journal={Physiological genomics},
  year={2001},
  volume={6 3},
  pages={
          169-81
        }
}

Alexander V. Loguinov, Lucy M. Anderson, +1 author Rustam Yu. Yukhananov

Published in Physiological genomics 2001

Biology, Medicine

The long-term response to neurotropic drugs depends on drug-induced neuroplasticity and underlying changes in gene expression. However, alterations in neuronal gene expression can be observed even following single injection. To investigate the extent of these changes, gene expression in the medial striatum and lumbar part of the spinal cord was monitored by cDNA microarray following single injection of morphine. Using robust and resistant linear regression (MM-estimator) with simultaneous… CONTINUE READING

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