Gene expression following acute morphine administration.

@article{Loguinov2001GeneEF,
  title={Gene expression following acute morphine administration.},
  author={A. Loguinov and L. Anderson and G. Crosby and R. Yukhananov},
  journal={Physiological genomics},
  year={2001},
  volume={6 3},
  pages={
          169-81
        }
}
The long-term response to neurotropic drugs depends on drug-induced neuroplasticity and underlying changes in gene expression. However, alterations in neuronal gene expression can be observed even following single injection. To investigate the extent of these changes, gene expression in the medial striatum and lumbar part of the spinal cord was monitored by cDNA microarray following single injection of morphine. Using robust and resistant linear regression (MM-estimator) with simultaneous… Expand
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