Gene expression during development of fetal and adult Leydig cells.

  title={Gene expression during development of fetal and adult Leydig cells.},
  author={Lei Dong and Scott A Jelinsky and Joshua N Finger and D. St Johnston and Gregory S. Kopf and Chantal M Sottas and Matthew Philip Hardy and Ren-Shan Ge},
  journal={Annals of the New York Academy of Sciences},
In rats and mice, Leydig cells are formed as two morphologically and functionally different generations. The first generation develops in utero, from undifferentiated stem Leydig cells (SLCs) that differentiate into fetal Leydig cells (FLCs). After birth, SLCs that may differ from the fetal SLCs undergo lineage-specific commitment and give rise to adult Leydig cells (ALCs). The intermediates of ALCs first become apparent by day 11 postpartum. These first-appearing intermediates, progenitor… CONTINUE READING


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