Gene expression correlates of clinical prostate cancer behavior.

  title={Gene expression correlates of clinical prostate cancer behavior.},
  author={Dinesh Singh and Phillip G. Febbo and Kenneth Ross and Donald G. Jackson and Judith B. Manola and Christine M Ladd and Pablo Tamayo and Andrew A Renshaw and Anthony V. D'Amico and Jerome P. Richie and Eric S. Lander and Massimo F. Loda and Philip W. Kantoff and Todd R. Golub and William R Sellers},
  journal={Cancer cell},
  volume={1 2},
Prostate tumors are among the most heterogeneous of cancers, both histologically and clinically. Microarray expression analysis was used to determine whether global biological differences underlie common pathological features of prostate cancer and to identify genes that might anticipate the clinical behavior of this disease. While no expression correlates of age, serum prostate specific antigen (PSA), and measures of local invasion were found, a set of genes was identified that strongly… CONTINUE READING
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