Gene expression and promoter polymorphisms of DNA methyltransferase 3B in nasopharyngeal carcinomas in Taiwanese people: a case-control study.

@article{Chang2008GeneEA,
  title={Gene expression and promoter polymorphisms of DNA methyltransferase 3B in nasopharyngeal carcinomas in Taiwanese people: a case-control study.},
  author={Kai-Ping Chang and Sheng-po Hao and Ngan-Ming Tsang and Y Chang and Ming-Huei Cheng and Chun-Ting Liu and Yun-Shien Lee and Chia-Lung Tsai and T Lee and Tzu-Hao Wang and Chi-Neu Tsai},
  journal={Oncology reports},
  year={2008},
  volume={19 1},
  pages={217-22}
}
Overexpression of the DNA methyltransferase 3B (DNMT3B) gene and its effect on carcinogenesis has been demonstrated for various types of cancer. Recently, three single nucleotide polymorphisms (SNPs) of the DNMT3B promoter region, C46359T (-149C>T), -283T>C, and -579G>T have also been reported to be stratification markers that can predict an individual's susceptibility to cancers. In this study, we analyzed expression of DNMT3B in nasopharyngeal carcinoma (NPC) specimens and did not find… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Similar Papers

Loading similar papers…