Gene expression and gene therapy imaging

  title={Gene expression and gene therapy imaging},
  author={Claire Rome and Franck Couillaud and Chrit Moonen},
  journal={European Radiology},
The fast growing field of molecular imaging has achieved major advances in imaging gene expression, an important element of gene therapy. Gene expression imaging is based on specific probes or contrast agents that allow either direct or indirect spatio-temporal evaluation of gene expression. Direct evaluation is possible with, for example, contrast agents that bind directly to a specific target (e.g., receptor). Indirect evaluation may be achieved by using specific substrate probes for a target… CONTINUE READING

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