Gene expression analysis with the parametric bootstrap.

@article{Laan2001GeneEA,
  title={Gene expression analysis with the parametric bootstrap.},
  author={Mark J van der Laan and Jenny Bryan},
  journal={Biostatistics},
  year={2001},
  volume={2 4},
  pages={445-61}
}
Recent developments in microarray technology make it possible to capture the gene expression profiles for thousands of genes at once. With this data researchers are tackling problems ranging from the identification of 'cancer genes' to the formidable task of adding functional annotations to our rapidly growing gene databases. Specific research questions suggest patterns of gene expression that are interesting and informative: for instance, genes with large variance or groups of genes that are… CONTINUE READING
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Gene expression analysis with the parametric bootstrap

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