Gene expression analysis of synovial tissue biopsies obtained from rheumatoid arthritis patients prior to infliximab treatment

@inproceedings{Lindberg2008GeneEA,
  title={Gene expression analysis of synovial tissue biopsies obtained from rheumatoid arthritis patients prior to infliximab treatment},
  author={Johan Lindberg and Carla A. Wijbrandts and Lisa G. van Baarsen and Gustavo Nader and Lars Klareskog and Anca Irinel Catrina and Rogier M. Thurlings and Margriet J.B.M. Vervoordeldonk and Joakim Lundeberg and Prashant P. Tak},
  year={2008}
}
In the studies this thesis is based upon, microarrays were applied to profilemRNA populations in biological samples to gain insights into transcriptionalpatterns and their relation to inflammatory disease.Rheumatoid arthritis (RA) is a chronic inflammatory disease, which leads todegradation of cartilage and bone. RA is characterized by synovial inflammationwith varying levels of tissue heterogeneity. This was confirmed by microarrayanalyses of multiple biopsies from the joints of 13 patients… CONTINUE READING

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