Gene expression analysis of angioimmunoblastic lymphoma indicates derivation from T follicular helper cells and vascular endothelial growth factor deregulation.

@article{Piccaluga2007GeneEA,
  title={Gene expression analysis of angioimmunoblastic lymphoma indicates derivation from T follicular helper cells and vascular endothelial growth factor deregulation.},
  author={Pier Paolo Piccaluga and Claudio Agostinelli and Andrea Califano and Antonino Carbone and Luca I Fantoni and Sergio Ferrari and Anna Gazzola and Annunziata Gloghini and Simona Righi and Maura Rossi and Enrico Tagliafico and Pier Luigi Zinzani and Simonetta Zupo and Michele Baccarani and Stefano A Pileri},
  journal={Cancer research},
  year={2007},
  volume={67 22},
  pages={
          10703-10
        }
}
Angioimmunoblastic lymphoma (AILT) is the second most common subtype of peripheral T-cell lymphoma (PTCL) and is characterized by dismal prognosis. Thus far, only a few studies have dealt with its molecular pathogenesis. We performed gene expression profile (GEP) analysis of six AILT, six anaplastic large cell lymphomas (ALCL), 28 PTCL-unspecified (PTCL/U), and 20 samples of normal T lymphocytes (including CD4(+), CD8(+), and activated and resting subpopulations), aiming to (a) assess the… CONTINUE READING

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p53-independent induction of Gadd45 by histone deacetylase inhibitor: 10 P.P. Piccaluga and S.A. Pileri, unpublished data. Gene Expression Analysis of AILT www.aacrjournals.org

  • T Hirose, Y Sowa, S Takahashi
  • Cancer Res
  • 2007
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