Gene expression abnormalities in histologically normal breast epithelium of breast cancer patients.

@article{Tripathi2008GeneEA,
  title={Gene expression abnormalities in histologically normal breast epithelium of breast cancer patients.},
  author={Anusri Tripathi and Chialin King and Antonio de la Morenas and Victoria Kristina Perry and Bohdana Burke and Gregory A Antoine and Erwin F. Hirsch and Maureen T Kavanah and Jane E. Mendez and M. Stone and Norman P. Gerry and Marc E. Lenburg and Carol L. Rosenberg},
  journal={International journal of cancer},
  year={2008},
  volume={122 7},
  pages={1557-66}
}
Normal-appearing epithelium of cancer patients can harbor occult genetic abnormalities. Data comprehensively comparing gene expression between histologically normal breast epithelium of breast cancer patients and cancer-free controls are limited. The present study compares global gene expression between these groups. We performed microarrays using RNA from microdissected histologically normal terminal ductal-lobular units (TDLU) from 2 groups: (i) cancer normal (CN) (TDLUs adjacent to untreated… CONTINUE READING

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