Gene environment interaction studies in depression and suicidal behavior: An update

@article{Mandelli2013GeneEI,
  title={Gene environment interaction studies in depression and suicidal behavior: An update},
  author={Laura Mandelli and Alessandro Serretti},
  journal={Neuroscience & Biobehavioral Reviews},
  year={2013},
  volume={37},
  pages={2375-2397}
}
Increasing evidence supports the involvement of both heritable and environmental risk factors in major depression (MD) and suicidal behavior (SB). Studies investigating gene-environment interaction (G × E) may be useful for elucidating the role of biological mechanisms in the risk for mental disorders. In the present paper, we review the literature regarding the interaction between genes modulating brain functions and stressful life events in the etiology of MD and SB and discuss their… CONTINUE READING

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 68 CITATIONS, ESTIMATED 74% COVERAGE

Genetic variants in major depressive disorder: From pathophysiology to therapy

  • Pharmacology & therapeutics
  • 2019
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Genome‐wide gene‐environment interaction in depression: A systematic evaluation of candidate genes The childhood trauma working‐group of PGC‐MDD

  • American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
  • 2018
VIEW 4 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

The influence of the serotonin transporter gene 5-HTTLPR polymorphism on suicidal behaviors: a meta-analysis

  • Progress in Neuro-Psychopharmacology and Biological Psychiatry
  • 2019
VIEW 2 EXCERPTS
CITES RESULTS & BACKGROUND

FILTER CITATIONS BY YEAR

2013
2019

CITATION STATISTICS

  • 2 Highly Influenced Citations

  • Averaged 12 Citations per year from 2017 through 2019