Gene-environment interaction of ApoE genotype and combat exposure on PTSD.


Factors determining who develops PTSD following trauma are not well understood. The €4 allele of the apolipoprotein E (apoE) gene is associated with dementia and unfavorable outcome following brain insult. PTSD is also associated with dementia. Given evidence that psychological trauma adversely affects the brain, we hypothesized that the apoE genotype… (More)
DOI: 10.1002/ajmg.b.32154