Gene-engineered T cells as a superior adjuvant therapy for metastatic cancer.


The major limiting factor in the successful application of adjuvant therapy for metastatic disease is the lack of adjuvant specificity that leads to severe side effects. Reasoning that T cells of the immune system are highly specific, we generated tumor-specific T cells by genetic modification of mouse primary T cells with a chimeric receptor reactive with… (More)


7 Figures and Tables

Slides referencing similar topics