Gene-editing nucleases

  title={Gene-editing nucleases},
  author={M. Baker},
  journal={Nature Methods},
  • M. Baker
  • Published 2011
  • Biology, Medicine
  • Nature Methods
ways to modify sequences in the genome, a powerful technique. Even as the genome sequences of many organisms are being revealed, understanding what those genes really do requires tweaking the sequences, deleting or modifying genes, and studying the consequences. With the exceptions of those from mice and yeast, however, eukaryotic genomes generally resist this type of precise tinkering. Engineered gene-editing nucleases are now poised to change that. Over the past 15 years, researchers have… Expand
TALENs: customizable molecular DNA scissors for genome engineering of plants.
  • Kunling Chen, C. Gao
  • Biology, Medicine
  • Journal of genetics and genomics = Yi chuan xue bao
  • 2013
Technology developments in biological tools for targeted genome surgery
Simple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome
An efficient TALEN mutagenesis system in rice.
Targeted Gene Mutation in Plants