Gene dosage of the common variant 9p21 predicts severity of coronary artery disease.

@article{Dandona2010GeneDO,
  title={Gene dosage of the common variant 9p21 predicts severity of coronary artery disease.},
  author={Sonny Dandona and Alexandre F. R. Stewart and Li Chen and Kathryn A P Williams and Derek So and Edward H. O'Brien and Christopher J Glover and Michel Lemay and Olivia Assogba and Lan Vo and Yan Qing Wang and Marino Labinaz and George A Wells and Ruth Mcpherson and Robert Roberts},
  journal={Journal of the American College of Cardiology},
  year={2010},
  volume={56 6},
  pages={479-86}
}
OBJECTIVES The purpose of this study was to test the hypothesis that 9p21 gene dosage determines the severity of coronary artery disease (CAD). BACKGROUND The 9p21 locus is the first common genetic variant to associate with risk of CAD and/or myocardial infarction in multiple studies. METHODS A cross-sectional study examined nondiabetic patients with… CONTINUE READING