Gene delivery into prostate cancer cells by holmium laser application

Abstract

New approaches to treat prostate cancer (PCA) are utilizing gene therapy and aim to correct the disease at the genetic level. Getting a gene efficiently into the target cell is the subject of much interest. We used a holmium laser for transfecting rat PCA cells with the reporter gene pEGFP. By FACS analysis and fluorescence microscopy, we could demonstrate… (More)
DOI: 10.1038/sj.pcan.4500653

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