Gene copy number variation throughout the Plasmodium falciparum genome

@inproceedings{Cheeseman2009GeneCN,
  title={Gene copy number variation throughout the Plasmodium falciparum genome},
  author={Ian H. Cheeseman and Natalia Gomez-Escobar and C{\'e}line Karine Carret and Alasdair C. Ivens and Lindsay B Stewart and Kevin K A Tetteh and David J Conway},
  booktitle={BMC Genomics},
  year={2009}
}
Gene copy number variation (CNV) is responsible for several important phenotypes of the malaria parasite Plasmodium falciparum, including drug resistance, loss of infected erythrocyte cytoadherence and alteration of receptor usage for erythrocyte invasion. Despite the known effects of CNV, little is known about its extent throughout the genome. We performed a whole-genome survey of CNV genes in P. falciparum using comparative genome hybridisation of a diverse set of 16 laboratory culture… CONTINUE READING