Gene conversion of major histocompatibility complex genes is associated with CpG-rich regions

@article{Hgstrand1999GeneCO,
  title={Gene conversion of major histocompatibility complex genes is associated with CpG-rich regions},
  author={Kari H{\"o}gstrand and Jan B{\"o}hme},
  journal={Immunogenetics},
  year={1999},
  volume={49},
  pages={446-455}
}
 We examined 32 DNA sequences of mouse and human major histocompatibility complex (MHC) genes believed to have been subjected to gene conversion events. All regions of the mouse H2 genes as well as the human HLA genes which have been implied to be involved in gene conversion events had elevated levels of CpG dinucleotides, whereas the rest of the genes showed extensive CpG suppression. Mouse MHC genes which have been suspected but not directly implied to be involved in gene conversion events… CONTINUE READING
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