Gene carriers based on hexanediol diacrylate linked oligoethylenimine: effect of chemical structure of polymer on biological properties.

@article{Kloeckner2006GeneCB,
  title={Gene carriers based on hexanediol diacrylate linked oligoethylenimine: effect of chemical structure of polymer on biological properties.},
  author={Julia Kloeckner and Stefano Bruzzano and Manfred Ogris and Ernst Wagner},
  journal={Bioconjugate chemistry},
  year={2006},
  volume={17 5},
  pages={
          1339-45
        }
}
Two biodegradable polycations based on hexanediol diacrylate linked oligoethylenimine (OEI) were synthesized by applying different reaction temperatures, 20 degrees C (LT-OEI-HD) and 60 degrees C (HT-OEI-HD). Their structural properties were analyzed by NMR, FTIR, and SEC/MALLS (size exclusion chromatography coupled with multiangle laser light scattering detection). Reaction temperature strongly influenced molecular weight and ester/amide ratio and thus resulted in polycations with different… CONTINUE READING
BETA

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…