Gene-by-Diet Interactions Affect Serum 1,25-Dihydroxyvitamin D Levels in Male BXD Recombinant Inbred Mice.

Abstract

1,25-Dihydroxyvitamin D (1,25[OH]2D) regulates calcium (Ca), phosphate, and bone metabolism. Serum 1,25(OH)2D levels are reduced by low vitamin D status and high fibroblast growth factor 23 (FGF23) levels and increased by low Ca intake and high PTH levels. Natural genetic variation controls serum 25-hydroxyvitamin D (25[OH]D) levels, but it is unclear how… (More)
DOI: 10.1210/en.2015-1786

Topics

Cite this paper

@article{Fleet2016GenebyDietIA, title={Gene-by-Diet Interactions Affect Serum 1,25-Dihydroxyvitamin D Levels in Male BXD Recombinant Inbred Mice.}, author={James C. Fleet and Rebecca A Replogle and Perla C Reyes-Fernandez and Libo Wang and Min Zhang and Erica L. Clinkenbeard and Kenneth E. White}, journal={Endocrinology}, year={2016}, volume={157 2}, pages={470-81} }