Gene-based immunotherapy for human immunodeficiency virus infection and acquired immunodeficiency syndrome.

@article{Dropuli2006GenebasedIF,
  title={Gene-based immunotherapy for human immunodeficiency virus infection and acquired immunodeficiency syndrome.},
  author={Boro Dropuli{\'c} and Carl H June},
  journal={Human gene therapy},
  year={2006},
  volume={17 6},
  pages={577-88}
}
More than 40 million people are infected with human immunodeficiency virus (HIV), and a successful vaccine is at least a decade away. Although highly active antiretroviral therapy prolongs life, the maintenance of viral latency requires life-long treatment and results in cumulative toxicities and viral escape mutants. Gene therapy offers the promise to cure or prevent progressive HIV infection by interfering with HIV replication and CD4+ cell decline long term in the absence of chronic… CONTINUE READING
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