Gene-asbestos interaction in malignant pleural mesothelioma susceptibility.

@article{Tunesi2015GeneasbestosII,
  title={Gene-asbestos interaction in malignant pleural mesothelioma susceptibility.},
  author={Sara Tunesi and Daniela Ferrante and Dario Mirabelli and Silvano Andorno and Marta Betti and Giovanni Fiorito and Simonetta Guarrera and Elisabetta Casalone and Monica Neri and Donatella Ugolini and Stefano Bonassi and Giuseppe Matullo and Irma Dianzani and Corrado Magnani},
  journal={Carcinogenesis},
  year={2015},
  volume={36 10},
  pages={
          1129-35
        }
}
Asbestos exposure is the main risk factor for malignant pleural mesothelioma (MPM), a rare aggressive tumor. Nevertheless, on average less than 10% of subjects highly exposed to asbestos develop MPM, suggesting the possible involvement of other risk factors. To identify the genetic factors that may modulate the risk of MPM, we conducted a gene-environment interaction analysis including asbestos exposure and 15 single nucleotide polymorphisms (SNPs) previously identified through a genome-wide… 

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