Gene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localization.

@article{Morel2004GeneAP,
  title={Gene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localization.},
  author={Fabrice Morel and Claudine Rauch and Elise Petit and Am{\'e}lie Piton and Nathalie Th{\'e}ret and Brian Coles and Andr{\'e} Guillouzo},
  journal={The Journal of biological chemistry},
  year={2004},
  volume={279 16},
  pages={16246-53}
}
Kappa class glutathione S-transferase (GST) cDNA sequences have been identified in rat, mouse, and human. In the present study, we determined the structure and chromosomal location of the human GST Kappa 1 (hGSTK1) gene, characterized the protein, and demonstrated its subcellular localization. The human gene spans approximately 5 kb, has 8 exons, and maps onto chromosome 7q34. The 5'-flanking region lacks TATA or CCAAT boxes, but there is an initiator element overlapping the transcription start… CONTINUE READING

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