Gene and microRNA expression signatures of human mesenchymal stromal cells in comparison to fibroblasts

@article{Bae2008GeneAM,
  title={Gene and microRNA expression signatures of human mesenchymal stromal cells in comparison to fibroblasts},
  author={Sohyun Bae and Jung Hoon Ahn and Chae Woon Park and Hye Kyung Son and Keun-Soo Kim and N Lim and C Jeon and Hoeon Kim},
  journal={Cell and Tissue Research},
  year={2008},
  volume={335},
  pages={565-573}
}
Human mesenchymal stromal cells (MSCs) offer great hope for the treatment of tissue degenerative and immune diseases, but their phenotypic similarity to dermal fibroblasts may hinder robust cell identification and isolation from diverse tissue harvests. To identify genetic elements that can reliably discriminate MSCs from fibroblasts, we performed comparative gene and microRNA expression profiling analyses with genome-wide oligonucleotide microarrays. When taken globally, both gene and microRNA… CONTINUE READING

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