Gene and miRNA expression profiles in autism spectrum disorders

  title={Gene and miRNA expression profiles in autism spectrum disorders},
  author={Mohammad Mahdi Ghahramani Seno and Pingzhao Hu and Fuad G. Gwadry and Dalila Pinto and Stephen W. Scherer},
  journal={Brain Research},
Accumulating data indicate that there is significant genetic heterogeneity underlying the etiology in individuals diagnosed with autism spectrum disorder (ASD). Some rare and highly-penetrant gene variants and copy number variation (CNV) regions including NLGN3, NLGN4, NRXN1, SHANK2, SHANK3, PTCHD1, 1q21.1, maternally-inherited duplication of 15q11-q13, 16p11.2, amongst others, have been identified to be involved in ASD. Genome-wide association studies have identified other apparently low risk… CONTINUE READING


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