Gene and cell-replacement therapy in the treatment of type 1 diabetes: how high must the standards be set?

@article{Halban2001GeneAC,
  title={Gene and cell-replacement therapy in the treatment of type 1 diabetes: how high must the standards be set?},
  author={Philippe A. Halban and Steven E Kahn and A Lernmark and Christopher J Rhodes},
  journal={Diabetes},
  year={2001},
  volume={50 10},
  pages={
          2181-91
        }
}
Recent advances in molecular and cell biology may allow for the development of novel strategies for the treatment and cure of type 1 diabetes. In particular, it is now possible to envisage restoration of insulin secretion by gene or cell-replacement therapy. The beta-cell is, however, remarkably sophisticated, and many of the features of this highly differentiated secretory cell will have to be faithfully mimicked in surrogate cells. In particular, insulin is normally secreted in a well… CONTINUE READING

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