Gene Therapy for Bone Defects in Oral and Maxillofacial Surgery: A Systematic Review and Meta-Analysis of Animal Studies.

@article{Fliefel2016GeneTF,
  title={Gene Therapy for Bone Defects in Oral and Maxillofacial Surgery: A Systematic Review and Meta-Analysis of Animal Studies.},
  author={Riham M Fliefel and Jan K{\"u}hnisch and Mildred Ehrenfeld and Sylvia Otto},
  journal={Stem cells and development},
  year={2016},
  volume={26 4},
  pages={
          215-230
        }
}
Craniofacial bone defects are challenging problems for maxillofacial surgeons over the years. With the development of cell and molecular biology, gene therapy is a breaking new technology with the aim of regenerating tissues by acting as a delivery system for therapeutic genes in the craniofacial region rather than treating genetic disorders. A systematic review was conducted summarizing the articles reporting gene therapy in maxillofacial surgery to answer the question: Was gene therapy… CONTINUE READING
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