Gene Therapy Strategies for HIV/AIDS: Preclinical Modeling in Humanized Mice

@inproceedings{Bennett2013GeneTS,
  title={Gene Therapy Strategies for HIV/AIDS: Preclinical Modeling in Humanized Mice},
  author={Michael S. Bennett and Ramesh Akkina},
  booktitle={Viruses},
  year={2013}
}
In the absence of an effective vaccine and lack of a complete cure, gene therapy approaches to control HIV infection offer feasible alternatives. Due to the chronic nature of infection, a wide window of opportunity exists to gene modify the HIV susceptible cells that continuously arise from the bone marrow source. To evaluate promising gene therapy approaches that employ various anti-HIV therapeutic molecules, an ideal animal model is necessary to generate important efficacy and preclinical… CONTINUE READING

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