Gene Therapy Death Prompts Review of Adenovirus Vector

@article{Marshall1999GeneTD,
  title={Gene Therapy Death Prompts Review of Adenovirus Vector},
  author={E. Marshall},
  journal={Science},
  year={1999},
  volume={286},
  pages={2244 - 2245}
}
  • E. Marshall
  • Published 1999
  • Medicine
  • Science
  • For the past 3 months, faculty and staff members at the University of Pennsylvania9s Institute for Human Gene Therapy have been trying to understand why a relatively fit 18-year-old with an inherited enzyme deficiency died on 17 September, 4 days after doctors at Penn injected a genetically altered virus into his liver. Last week, they presented their data to a government advisory committee. The patient was the first in a gene therapy trial to die of the therapy itself; his death is the latest… CONTINUE READING

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