Gene Regulatory Network Interactions in Sea Urchin Endomesoderm Induction

  title={Gene Regulatory Network Interactions in Sea Urchin Endomesoderm Induction},
  author={A. Sethi and R. Angerer and L. Angerer},
  journal={PLoS Biology},
  • A. Sethi, R. Angerer, L. Angerer
  • Published 2009
  • Biology, Medicine
  • PLoS Biology
  • A major goal of contemporary studies of embryonic development is to understand large sets of regulatory changes that accompany the phenomenon of embryonic induction. The highly resolved sea urchin pregastrular endomesoderm–gene regulatory network (EM-GRN) provides a unique framework to study the global regulatory interactions underlying endomesoderm induction. Vegetal micromeres of the sea urchin embryo constitute a classic endomesoderm signaling center, whose potential to induce archenteron… CONTINUE READING

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