Gene Regulatory Network Interactions in Sea Urchin Endomesoderm Induction

@article{Sethi2009GeneRN,
  title={Gene Regulatory Network Interactions in Sea Urchin Endomesoderm Induction},
  author={Aditya J. Sethi and Robert C. Angerer and Lynne M. Angerer},
  journal={PLoS Biology},
  year={2009},
  volume={7},
  pages={449 - 462}
}
A major goal of contemporary studies of embryonic development is to understand large sets of regulatory changes that accompany the phenomenon of embryonic induction. The highly resolved sea urchin pregastrular endomesoderm-gene regulatory network (EM-GRN) provides a unique framework to study the global regulatory interactions underlying endomesoderm induction. Vegetal micromeres of the sea urchin embryo constitute a classic endomesoderm signaling center, whose potential to induce archenteron… CONTINUE READING
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