Gene Regulation in Primates Evolves under Tissue-Specific Selection Pressures

Abstract

Regulatory changes have long been hypothesized to play an important role in primate evolution. To identify adaptive regulatory changes in humans, we performed a genome-wide survey for genes in which regulation has likely evolved under natural selection. To do so, we used a multi-species microarray to measure gene expression levels in livers, kidneys, and… (More)
DOI: 10.1371/journal.pgen.1000271

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