Gene Recombination in Escherichia Coli

  title={Gene Recombination in Escherichia Coli},
  author={Joshua Lederberg and Edward L. Tatum},
ANALYSIS of mixed cultures of nutritional mutants has revealed the presence of new types which strongly suggest the occurrence of a sexual process in the bacterium, Escherichia coli. 

Bacterial Conjugation A Historical Perspective

The phenomenon of conjugation in bacteria provides one of the cornerstones of bacterial genetics. Use of the technology led to our initial understanding of the circular bacterial chromosome carrying


  • S. Luria
  • Medicine
    Bacteriological reviews
  • 1947
In this lengthy article, Luria provided a thorough overview of the state of research on bacterial genetics in 1947.

A transduction-like process within a single strain of Pseudomonas aeruginosa.

  • J. Loutit
  • Biology
    Journal of general microbiology
  • 1958
SUMMARY: A process of genetic transfer, which could be demonstrated with culture filtrates of a strain of Pseudomonas aeruginosa, is described. The evidence indicates that genetic material was

Bacterial Genetic Exchange

Exchange of genetic material between bacterial species is mediated by the basic processes of conjugation, transduction and transformation. This exchange is fundamental for bacterial evolution and

Studies on bacterial conjugational crosses via model populations. I. The model populations.

  • L. Alföldi
  • Biology
    Acta microbiologica et immunologica Hungarica
  • 2004
A procedure is presented in which model populations, simulating progenies obtained from Escherichia coli Hfr x F- crosses, are generated. The procedure seems to be appropriate for visualizing hidden

Optimzing the 5'-end of Coding Sequences in Recombinant mRNA to achieve high-level Expression in the Bacterium Escherichia coli

Recombinant protein production in Escherichia coli provides a cheap and efficient way of producing medically and industrially relevant proteins. Sequence features of individual genes and especiall ...

Tn916-mediated plasmid transfer in Bacillus subtilis

A comparison of comparative transport systems using Tn916 and Tn925 as an example shows that the former is a more efficient system and the latter is a less efficient system.



Mutations of Bacteria from Virus Sensitivity to Virus Resistance.

This article reported Luria and Delbruck's breakthrough study in which they established that viruses do not induce mutations in bacteria, but that virus-resisting mutations are spontaneous. Their

X-Ray Induced Mutant Strains of Escherichia Coli.

  • E. Tatum
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1945

Versl . A & f . Wemsch

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93 ([972). 3. Lederbers, J. & Tatum, E.L. Nature 1S8

  • 93 ([972). 3. Lederbers, J. & Tatum, E.L. Nature 1S8
  • 1946

A&f. Wemsch. (Amsterdam)

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