Gene Recombination in Escherichia Coli

  title={Gene Recombination in Escherichia Coli},
  author={Joshua Lederberg and Edward L. Tatum},
ANALYSIS of mixed cultures of nutritional mutants has revealed the presence of new types which strongly suggest the occurrence of a sexual process in the bacterium, Escherichia coli. 
Bacterial Conjugation A Historical Perspective
The phenomenon of conjugation in bacteria provides one of the cornerstones of bacterial genetics. Use of the technology led to our initial understanding of the circular bacterial chromosome carryingExpand
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SUMMARY: A process of genetic transfer, which could be demonstrated with culture filtrates of a strain of Pseudomonas aeruginosa, is described. The evidence indicates that genetic material wasExpand
Bacterial Genetic Exchange
Exchange of genetic material between bacterial species is mediated by the basic processes of conjugation, transduction and transformation. This exchange is fundamental for bacterial evolution andExpand
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A procedure is presented in which model populations, simulating progenies obtained from Escherichia coli Hfr x F- crosses, are generated. The procedure seems to be appropriate for visualizing hiddenExpand
The ecology of plasmid-coded antibiotic resistance: a basic framework for experimental research and modeling
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Graphical abstract
Optimzing the 5'-end of Coding Sequences in Recombinant mRNA to achieve high-level Expression in the Bacterium Escherichia coli
Recombinant protein production in Escherichia coli provides a cheap and efficient way of producing medically and industrially relevant proteins. Sequence features of individual genes and especiall ...
Tn916-mediated plasmid transfer in Bacillus subtilis
A comparison of comparative transport systems using Tn916 and Tn925 as an example shows that the former is a more efficient system and the latter is a less efficient system. Expand
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It is demonstrated that the origin of the complexities is located in the particular allelic configuration of the genotypes, characteristic for all exconjugant and selected populations. Expand


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This article reported Luria and Delbruck's breakthrough study in which they established that viruses do not induce mutations in bacteria, but that virus-resisting mutations are spontaneous. TheirExpand
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