Gene Polymorphism and Phenytoin Pharmacokinetics in Epilepsy

  title={Gene Polymorphism and Phenytoin Pharmacokinetics in Epilepsy},
  author={Adel A Alhazzani and Murali Munisamy and Gauthaman Karunakaran},
29 Epilepsy is considered one of the major public health problems and could have serious psychological and physical consequences, including mental health disorders, traumatic injury and premature death1. Epilepsy is a chronic and disabling neurologic disorder and affects approximately 1% of the population globally, especially in developing countries1,2. Although good prognosis has been seen in most patients with epilepsy, approximately 20% to 30% of patients with epilepsy do not remain seizure… CONTINUE READING