Gene PA2449 is essential for glycine metabolism and pyocyanin biosynthesis in Pseudomonas aeruginosa PAO1.

@article{Lundgren2013GenePI,
  title={Gene PA2449 is essential for glycine metabolism and pyocyanin biosynthesis in Pseudomonas aeruginosa PAO1.},
  author={Benjamin R. Lundgren and William Thornton and Mark H. Dornan and Luis Roberto Villegas-Pe{\~n}aranda and Christopher N. Boddy and Christopher T Nomura},
  journal={Journal of bacteriology},
  year={2013},
  volume={195 9},
  pages={2087-100}
}
Many pseudomonads produce redox active compounds called phenazines that function in a variety of biological processes. Phenazines are well known for their toxicity against non-phenazine-producing organisms, which allows them to serve as crucial biocontrol agents and virulence factors during infection. As for other secondary metabolites, conditions of nutritional stress or limitation stimulate the production of phenazines, but little is known of the molecular details underlying this phenomenon… CONTINUE READING