Gene Expression in Peripheral Blood Leukocytes in Monozygotic Twins Discordant for Chronic Fatigue: No Evidence of a Biomarker

@article{Byrnes2009GeneEI,
  title={Gene Expression in Peripheral Blood Leukocytes in Monozygotic Twins Discordant for Chronic Fatigue: No Evidence of a Biomarker},
  author={Andrea Byrnes and Andreas Jacks and Karin Dahlman-Wright and Birgitta Eveng{\aa}rd and Fred A. Wright and Nancy L Pedersen and Patrick F. Sullivan},
  journal={PLoS ONE},
  year={2009},
  volume={4},
  pages={953 - 959}
}
BACKGROUND Chronic fatiguing illness remains a poorly understood syndrome of unknown pathogenesis. We attempted to identify biomarkers for chronic fatiguing illness using microarrays to query the transcriptome in peripheral blood leukocytes. METHODS Cases were 44 individuals who were clinically evaluated and found to meet standard international criteria for chronic fatigue syndrome or idiopathic chronic fatigue, and controls were their monozygotic co-twins who were clinically evaluated and… CONTINUE READING
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